‰ ———————————————————————————————————————————————————————————————— • \laptop\sequeris\tests.txt & tracing, therapy, antibodies, immunity, T-cells peptide.txt serology.txt name="vaccinated" mild symptoms https://www.bbc.com/news/uk-57874744 received both vaccine doses, confirmed the positive result stopping symptomatic disease from the Delta variant: two doses of the AstraZeneca vaccine was 60% effective Two jabs of the Pfizer vaccine was 88% effective. Lateral flow tests provide a quick result, intended for use in those without symptoms PCR tests used when there are coronavirus symptoms or already have had a positive lateral flow result name="types" Molecular test (aka RNA or PCR test) · Antigen test (aka rapid test) · Antibody test (aka serology test or blood test) https://www.health.com/condition/infectious-diseases/coronavirus/covid-19-test-types https://www.dshs.state.tx.us/coronavirus/docs/COVID19-TestingExplained.pdf https://www.abbott.com/corpnewsroom/diagnostics-testing/covid-19-the-different-tests-explained.html https://www.cnn.com/2020/04/28/us/coronavirus-testing-pcr-antigen-antibody/index.html https://www.fda.gov/consumers/consumer-updates/coronavirus-disease-2019-testing-basics §§§ TESTS antigen tests - tests that tell you if someone currently has coronavirus https://www.fda.gov/consumers/consumer-updates/coronavirus-testing-basics molecular, antigen, antibody https://abc7news.com/coronavirus-test-testing-covid19-what-are-the-different-tests-for/6196119/ genetic, antigen, antibody name="antigen" https://upload.wikimedia.org/wikipedia/commons/thumb/8/82/COVID-19_rapid_test.jpg/290px-COVID-19_rapid_test.jpg https://en.wikipedia.org/wiki/Rapid_antigen_test https://www.hsph.harvard.edu/news/features/coronavirus-covid-19-press-conference-with-michael-mina-02-05-21/ https://www.hsph.harvard.edu/news/hsph-in-the-news/expert-frustrated-at-lack-of-rapid-at-home-covid-19-tests/ name="home" https://www.bbc.com/news/av/health-56326456 instructions video https://www.ellumehealth.com/products/consumer-products/covid-home-test User-friendly mid-turbinate Nasal Swab HIPAA compliant cloud connection Bluetooth connected Analyzer ChicagoTribune 2020December17 s2p1 rapidFDAok AbdelJimenez Ellume approved Dec 15 $30 test with results in20min without prescription Lucira Health approved Nov 12 Abbott BinaxNOW 30million in first quarter of 2021 $25 Dr Partice Harris, CEO, eMed Abbott's smartphone app Navica: take test during video session ChicagoTribune 2020December16 s2p11 homeTest MatthewPerrone,AP Ellume, Australia $30 3M nest month smartphone bluetooth app Stephen Hahn, FDA commissioner other one requires a physicians prescription 25 different tests can be done at home but need to be shipped to a lab https://www.nytimes.com/2020/12/15/health/rapid-covid-test-ellume.html New At-Home Covid Test Gets Green Light From F.D.A. data is pinged to a smartphone via Bluetooth. ChicagoTribune 2021October76 s2p4 homeTestRecalled https://www.ellumehealth.com/ 1/4 of positives false, no flase negatives https://innovamedgroup.com/ manufacture and distribution of rapid antigen and antibody test kits 800 E. Colorado Blvd., Suite 288, Pasadena, CA 91101, USA https://www.oneillinois.com/stories/2020/8/19/uiuc-saliva-covid-test-okd-by-fda Gov. Pritzker: game changer August 19, 2020 results in three to six hours at a cost of $10 a test Dr. Marty Burke, UIUC chemistry professor ChicagoTribune 2020August23 s1p12 casestoMultiply ElyssaCherney Nigel Goldenfeld, physics professor two to six hours https://www.abbott.com/IDNOW.html https://www.abbott.com/corpnewsroom/diagnostics-testing/detect-covid-19-in-as-little-as-5-minutes.html https://www.dailymail.co.uk/health/article-8241057/Abbotts-5-minute-coronavirus-test-producing-false-negative-results-15-time-study-finds.html https://www.npr.org/sections/health-shots/2020/04/21/838794281/study-raises-questions-about-false-negatives-from-quick-covid-19-test https://www.lucirahealth.com/ https://www.ideastream.org/news/cleveland-clinic-assists-with-first-at-home-covid-19-test-approved-by-fda https://www.npr.org/2020/11/18/936342944/fda-approves-coronavirus-test-that-can-be-administered-at-home FDA Approves Coronavirus Test That Can Be Administered At Home going to cost about $50 Within about 30 minutes, a light flashes either positive or negative Dr. Gary Procop at the Cleveland Clinic Dr. Michael Mina, Harvard T.H. Chan School of Public Health https://www.npr.org/sections/coronavirus-live-updates/2020/11/17/936055284/fda-approves-first-at-home-coronavirus-test FDA Approves 1st At-Home Coronavirus Test https://www.bbc.com/news/health-53131237 'Do it at home' coronavirus saliva test trialled name="tests" https://www.bloomberg.com/news/articles/2020-05-09/fda-authorizes-quidel-s-antigen-test-first-of-its-kind-in-u-s https://www.wsj.com/articles/fda-to-grant-emergency-use-status-for-first-coronavirus-antigen-test-by-quidel-corp-11589031815 https://ir.quidel.com/Coronavirus/default.aspx San Diego, CA https://www.bbc.com/news/uk-53632043 New 90-minute tests for Covid-19 and flu 'hugely beneficial' LamPORE from DnaNudge https://www.imperial.ac.uk/news/201073/90-minute-covid-19-tests-government-orders/ ChicagoTribune 2020April14 section 1 page 8 MatthewPerrone, AP US clears 1st saliva test to help detect virus Andrew Brooks, Rutgers one lab can process 10,000 patient samples per day Spectrum Solutios, Draper, Utah similar devices for DNA-based ancestry testing services ChicagoTribune 2020Auguust24 s1p12 IsrealAlgorithm DavidMHalfinger NYTimes 12 labs by October Ronen Walfisch, Defense Ministry Moran Szwarcewort Cohen, Rambam Health Care Campus, Haifa Dorfman method combinatorial algorithm Noam Shental, Open University of Israel ScienceAdvances Tomer Hertz, Angel Porgador, Ben Gurion Univ of Negev P-Best Pooling-Based Efficient SARS-CoV-2 Testing 384, 48 pools, unique set of six Poold Diagnostics usefullness drops as positives exceed expected Michael Lebowitz, science officer, 20/20 GeneSystems, Rockville, MD https://www.fda.gov/news-events/press-announcements/coronavirus-covid-19-update- fda-issues-emergency-use-authorization-yale-school-public-health FDA Issues Emergency Use Authorization to Yale School of Public Health for SalivaDirect, Which Uses a New Method of Saliva Sample Processing ChicagoTribune2020April6s1p10 No virus home test. MatthewPerrone, AP 100,000/day threshold needed to track the virus "The idea behind both tests is the same: chemical solutions are used to isolate the virus from the patient sample, grab its genetic material and then reproduce it millions of times until it's detectable with a computer." Dr. Bobbi Pritt, MayoClinic only a health care professional can order a test. shipping it to a lab within three days "at home kits will be required to be shown comparable", Jeremy Kahn, FDA https://www.bbc.com/news/business-52276836 The scientists who made a 'home-brew' coronavirus test Qiagen, Roche, Merck and Eurofins Genomics designed for specific models of the PCR machines. https://www.crick.ac.uk/research/covid-19/covid19-consortium ribonucleic acid Enzymes called proteases chemical cocktail allows the virus RNA code in the PCR machine to reproduce itself covered in fluorescent chemicals and copies are made Qiagen, a German chemicals company: playing with fire Roche agrees "These kits are all corporate secrets" «««««« «««««««««« «««««««««« «««««««««« »»»»»»»»»» »»»»»»»»»» »»»»»»»»»» »»»»»» name="smell" ChicagoTribune 2020November18 s5p2 smellScreen StacyBurling, The Philadelphia Inquirer NancyRawson, Monell Chemical Senses Center 77% of patients have smell loss one of the earliest symptoms wine may taste like vinegar Scentinel, olfactory disfunction test Scentisphere three peel-and-snitt films, one of three films has: coffee,chocolate,poipcorn,methylMercaptin,... detect neurodegeneration with $1 test COVID-19 appears to bind to ACE2 Smell and Taste Association of North America JAMA Otolaryngology: over 65 with impaired smell more likely to die within 5 years advanced physiological aging «««««« «««««««««« «««««««««« «««««««««« »»»»»»»»»» »»»»»»»»»» »»»»»»»»»» »»»»»» name="successes" https://www.npr.org/2020/03/25/821591044/behind-germanys-relatively-low-covid-19-fatality-rate https://www.npr.org/2020/03/25/820595489/why-germanys-coronavirus-death-rate-is-far-lower-than-in-other-countries part 1 testing 2 tracing 3 ... 4 Christian Drosten, director of the institute of virology at Berlin's Charité hospital Lothar Wieler, Robert Koch Institute https://en.wikipedia.org/wiki/COVID-19_pandemic_in_Germany https://www.bbc.com/news/technology-52681464 Can we learn about coronavirus-tracing from South Korea? https://www.bbc.com/news/world-australia-52703265 Scott Morrison: Australia's PM fewer than 100 deaths and around 7,000 cases emergency cabinet with the eight state and territory leaders to make decisions good example in Wales: https://ichef.bbci.co.uk/news/624/cpsprodpb/171E/production/_112381950_deaths20may-nc.png name="list" ChicagoTribune 2021November24 s2p7 homeTesting MatthewPerrone, AP playing catchup NeilSehgal, U MD market leader Abbott 50M/month BinaxNow Acon Laboratories 13 now available https://en.wikipedia.org/wiki/COVID-19_testing https://en.wikipedia.org/wiki/COVID-19_testing_in_the_United_States#Types_of_testing https://en.wikipedia.org/wiki/List_of_COVID-19_vaccine_authorizations name="other" «««««« «««««««««« «««««««««« «««««««««« »»»»»»»»»» »»»»»»»»»» »»»»»»»»»» »»»»»» §§§ CONTACT TRACING tracing.txt https://www.npr.org/sections/health-shots/2020/04/10/831200054/cdc-director-very-aggressive-contact-tracing-needed-for-u-s-to-return-to-normal ChicagoTribune 2020April21 section 1 page 13 Health Insurance Portability and Accountability Act (HIPAA) Pentagon's Total Information Awareness project contact tracing; testing antibody testing to determine who can return to work McHenry County Department of Health Judge Michael Chmiel https://www.weisradio.com/experts-call-for-new-national-public-health-workforce-to-trace-spread-of-covid-19-cases/ https://www.inquirer.com/health/coronavirus/coronavirus-strategy-governors-20200410.html A plan to defeat coronavirus finally emerges, but it’s not from the White House Experts have proposed transforming the Peace Corps paying new hires roughly the same salary as census takers •••••••••••••••••••••••••••••••••••••••••••••••••••••••••••• ««««««««««««««««««««««««««««««««««««««««»»»»»»»»»»»»»»»»»»»»»»»»»»»»»»»»»»»»»»»» «««««« «««««««««« «««««««««« «««««««««« »»»»»»»»»» »»»»»»»»»» »»»»»»»»»» »»»»»» name="vaccine" https://www.bbc.com/news/business-52917118 begin making potential vaccine AstraZeneca Pascal Soriot know by August if the AZD1222 vaccine Serum Institute of India (SII) Coalition for Epidemic Preparedness Innovations (CEPI) GAVI vaccines alliance https://theconversation.com/researchers-seek-to-repurpose-an-existing-manufacturing-platform-to-produce-a-covid-19-vaccine-134216 https://csuventures.org/project/solavax-rapid-development-of-a-vaccine-for-covid-19/ in combination with ultraviolet light of specific wavelengths, B2 can alter genetic material «««««« «««««««««« «««««««««« «««««««««« »»»»»»»»»» »»»»»»»»»» »»»»»»»»»» »»»»»» https://www.bbc.com/news/health-52234061 Germany is preparing to start new tests next week to find out who has already had the coronavirus. The tests will look for antibodies in the blood, with the aim of working out infection rates. The immune system. Lindsay B. Nicholson https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5091071/ An effective immune system must be able to discriminate such differences distinguishing harmless non-self from dangerous non-self https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590614/ Primer on the Immune System Martin J. Spiering, Ph.D., ELS https://www.bbc.com/news/health-52446965 James Gallagher Health&science correspondent immunity: Can you catch it twice? adaptive response neutralising antibodies cellular immunity ??https://www.bbc.com/news/health-52530828 priming the mosquito's immune system antibodies can be ineffective https://www.sciencedaily.com/releases/2009/04/090422151832.htm Anti-HIV Antibodies Are Ineffective https://onlinelibrary.wiley.com/doi/full/10.1002/9781118596784.ssd001 Principles, Concepts and Strategies of Stereoselective Synthesis Vasyl Andrushko Natalia Andrushko Perhaps covid-19 is especially surreptitious in confusing the immune system. https://www.bbc.com/future/article/20200422-how-disease-outbreaks-are-contained «««««« «««««««««« «««««««««« «««««««««« »»»»»»»»»» »»»»»»»»»» »»»»»»»»»» »»»»»» https://courses.lumenlearning.com/microbiology/chapter/isolation-culture-and-identification-of-viruses/ People who have had the disease and tests positive for the antibodies will be especially valuable since they will be able to work closely with someone who isn't. https://www.theguardian.com/world/2020/apr/30/coronavirus-what-do-scientists-know-about-covid-19-so-far •••••••••••••••••••••••••••••••••••••••••••••••••••••••••••• Coronavirus pandemic: Tracking the global outbreak Coronavirus: How to understand the death toll •••••••••••••••••••••••••••••••••••••••••••••••••••••••••••• https://en.wikipedia.org/wiki/Healthcare_in_Germany the system is decentralized every treatment and performance has to be required, economic, sufficient and appropriate negotiated at the level of federal states https://en.wikipedia.org/wiki/States_of_Germany I wonder if enough electonic monitoring could make these people useful in work release? https://www.npr.org/sections/coronavirus-live-updates/2020/04/20/838943211/73-of-inmates-at-an-ohio-prison-test-positive-for-coronavirus Maybe dogs could be trained to keep them in line. Perhaps they should be given an extra year off of their sentence for going thru a coronavirus outbreak. If one state tries to reopen the economy prematurally, the other states should hold back to see what happens. A bad outcome of their impetuousness will end the inappropriate demonstrations. The question is, now that some people have been exposed, some have died, and some have recovered, how vulnerable are the remaining people? The fact that the number of new infections per day has not decreased indicates that there are plenty of people yet who have not been exposed. Switching factories from making automobiles to much smaller ventilators should make room for social distancing. ———————————————————————————————————————————————————————————————— • name="blood" name="cancer" https://grail.com/who-we-are/ 1525 O’Brien Drive Menlo Park, CA 94025 50 distinctive cancer types CancerSEEK assay and the PanSeer assay